The actress’ well-documented battle with multiple sclerosis has captured the sympathies of fans the world over, and though her health issues have no doubt been a huge struggle, Applegate continues to put on a brave face.

Last night (Monday, January 15) the 52-year-old took to the stage, aided by a cane, to present two awards at the Emmys, and her appearance was celebrated by those in attendance.

Applegate, best known for her roles in films such as Anchorman and TV series including Dead to Me, was helped across the stage by actor Anthony Anderson.

With the actress making her way to the podium, the audience at the Peacock Theater in Los Angeles collectively rose to their feet in support.

It was an emotional moment, and one that didn’t fail to make an impact on Applegate.

“Thank you so much! Oh my God!” she said.

“You’re totally shaming me [and my] disability by standing up.”

She added: “Some of you may know me as Kelly Bundy from Married with Children. We don’t have to applaud every time I do something.”

The Bad Moms actress concluded her speech by telling the audience: “I’m going to cry more than I’ve been crying.”

Unsurprisingly, Christina’s reception and the general appreciation for an inspiring woman who’s endured so much of late, struck a positive cord with fans watching from home.

“The standing ovation for Christina Applegate has me bawling already,” one fan wrote.

“I adore Christina Applegate,” another wrote. “She’s such an amazing comedic talent and absolutely gorgeous (always has been!). Her zings here are fire.”

“Man, that was a beautiful moment for Christina Applegate,” a third wrote.

“Randomly woke up at 4:30am and straight away saw that clip of the huge ovation for Christina Applegate. And now I’m going to have to cry myself back to sleep,” a fourth admitted.

Applegate revealed her MS diagnosis back in 2021, and admitted last year that the illness means she will likely not be able to act on camera anymore.

“With the disease of MS, it’s never a good day,” she told Vanity Fair. “Going down the stairs, carrying things—you can’t do that anymore. It f—ing sucks.”

She continued: “I’m probably not going to work on-camera again.”

“I can’t even imagine going to set right now. This is a progressive disease. I don’t know if I’m going to get worse. I can do voiceover stuff because I have to support my family and keep my brain working.”

Watch Christina Applegate’s tearjerking reception at the Emmys in the video below: